10 Nov.2026
YA-MAN Presents Research on Cosmetic Ingredient Delivery at the 36th IFSCC Congress
Study examines the delivery of oil-soluble cosmetic ingredients into the skin’s outermost layer using charged nanomicelles and electrical stimulation
YA-MAN LTD., a Japanese beauty device manufacturer headquartered in Tokyo, presented research at the 36th Congress of the International Federation of Societies of Cosmetic Chemists (IFSCC) in Perth, Australia. The study examined the use of charged nanomicelles and electrical stimulation to improve the delivery of retinyl palmitate into the skin’s outermost layer. YA-MAN has held the largest share of the Japanese facial care device market for eight consecutive years*¹.
■Research Background
As a beauty device manufacturer, YA-MAN is committed not only to developing facial care devices but also to advancing research into cosmetic formulations. Its research focuses on combining electrical stimulation from beauty devices with cosmetic ingredients to explore more efficient approaches to ingredient delivery.
Oil-soluble cosmetic ingredients generally conduct electricity poorly, making it difficult to enhance their delivery using electrical stimulation. To address this challenge, YA-MAN developed new charged nanomicelles—nanoscale particles that encapsulate oil-soluble cosmetic ingredients and have negatively charged surfaces. The researchers investigated whether this approach could efficiently enhance ingredient delivery into the stratum corneum, the skin’s outermost layer, even with gentle electrical stimulation intended for use in at-home facial care devices.
■Research Results
In a study involving 12 participants, YA-MAN investigated the delivery of retinyl palmitate into the stratum corneum using electrical stimulation and charged nanomicelles containing this oil-soluble cosmetic ingredient. With iontophoresis, the amount of retinyl palmitate in the stratum corneum was approximately 1.6 times that measured with topical application alone, showing a trend toward an increase. When electrical stimulation alternated between iontophoresis and YA-MAN’s proprietary composite waveform, the amount was approximately 2.1 times that measured with topical application alone, a statistically significant increase.
These results indicate that combining negatively charged nanomicelles with electrical stimulation can enhance the delivery of oil-soluble cosmetic ingredients into the stratum corneum, an effect that has traditionally been difficult to achieve using electrical stimulation. YA-MAN will continue to share advanced beauty technologies developed in Japan with the world, aiming to create new beauty experiences for people around the globe.
■ About YA-MAN YA-MAN is a Japanese beauty technology company that develops beauty devices and skincare. Its research explores how device technologies and cosmetic formulations can work together to support at-home beauty routines. For more information, visit ya-manusa.com.
Research Information
For additional background, read YA-MAN’s research summary on charged nanomicelles and electrical stimulation (Japanese).
https://www.hyojo-science.com/report/202
*¹ Based on manufacturers’ market shares in the Facial Care Device category of the Japanese beauty electronics market, as reported in Beauty & Health Appliances Marketing Trend Data 2020 (covering 2018–2019), Beauty & Health Appliances Market & Related Services Trend Data 2023–2024 (covering 2020–2023), and Skin & Hair Care Appliance Trend Data 2026 (covering 2024–2025). Based on annual performance data; figures for 2023 are estimates.
※The information in this announcement is current as of the release date and is subject to change.
YA-MAN LTD., a Japanese beauty device manufacturer headquartered in Tokyo, presented research at the 36th Congress of the International Federation of Societies of Cosmetic Chemists (IFSCC) in Perth, Australia. The study examined the use of charged nanomicelles and electrical stimulation to improve the delivery of retinyl palmitate into the skin’s outermost layer. YA-MAN has held the largest share of the Japanese facial care device market for eight consecutive years*¹.
■Research Background
As a beauty device manufacturer, YA-MAN is committed not only to developing facial care devices but also to advancing research into cosmetic formulations. Its research focuses on combining electrical stimulation from beauty devices with cosmetic ingredients to explore more efficient approaches to ingredient delivery.
Oil-soluble cosmetic ingredients generally conduct electricity poorly, making it difficult to enhance their delivery using electrical stimulation. To address this challenge, YA-MAN developed new charged nanomicelles—nanoscale particles that encapsulate oil-soluble cosmetic ingredients and have negatively charged surfaces. The researchers investigated whether this approach could efficiently enhance ingredient delivery into the stratum corneum, the skin’s outermost layer, even with gentle electrical stimulation intended for use in at-home facial care devices.
■Research Results
In a study involving 12 participants, YA-MAN investigated the delivery of retinyl palmitate into the stratum corneum using electrical stimulation and charged nanomicelles containing this oil-soluble cosmetic ingredient. With iontophoresis, the amount of retinyl palmitate in the stratum corneum was approximately 1.6 times that measured with topical application alone, showing a trend toward an increase. When electrical stimulation alternated between iontophoresis and YA-MAN’s proprietary composite waveform, the amount was approximately 2.1 times that measured with topical application alone, a statistically significant increase.
These results indicate that combining negatively charged nanomicelles with electrical stimulation can enhance the delivery of oil-soluble cosmetic ingredients into the stratum corneum, an effect that has traditionally been difficult to achieve using electrical stimulation. YA-MAN will continue to share advanced beauty technologies developed in Japan with the world, aiming to create new beauty experiences for people around the globe.
■ About YA-MAN YA-MAN is a Japanese beauty technology company that develops beauty devices and skincare. Its research explores how device technologies and cosmetic formulations can work together to support at-home beauty routines. For more information, visit ya-manusa.com.
Research Information
For additional background, read YA-MAN’s research summary on charged nanomicelles and electrical stimulation (Japanese).
https://www.hyojo-science.com/report/202
*¹ Based on manufacturers’ market shares in the Facial Care Device category of the Japanese beauty electronics market, as reported in Beauty & Health Appliances Marketing Trend Data 2020 (covering 2018–2019), Beauty & Health Appliances Market & Related Services Trend Data 2023–2024 (covering 2020–2023), and Skin & Hair Care Appliance Trend Data 2026 (covering 2024–2025). Based on annual performance data; figures for 2023 are estimates.
※The information in this announcement is current as of the release date and is subject to change.
